Katrina Steiling, MD, MSc

Assistant Professor of Medicine and Bioinformatics
Boston University School of Medicine


phone: (617)414-6996


Research Interests:

My research involves gene expression profiling of the large airway epithelium in smokers with chronic obstructive pulmonary disease (COPD) and lung cancer in order to provide insights into the molecular mechanisms of COPD and the relationship between COPD and lung cancer. 


Selected Publications:

Steiling K, Berge M, Sebastiani P, O'Connor G, Zhang X, Liu G, Xiao J, Alekseyev Y, Campbell J, Coxson HO, Hogg JC, McWilliams A, Timens W, Hiemstra PS, Sterk PJ, Sin D, Postma D, Lam S, Lenburg ME, Spira A. "Airway gene expression as a molecular phenotype of COPD." Proc Am Thorac Soc, 2011; 8(2): 208.


Gower AC, Steiling K, Brothers JF 2nd, Lenburg ME, Spira A. "Transcriptomic studies of the airway field of injury associated with smoking-related lung disease." Proc Am Thorac Soc, 2011; 8(2):173-9


Brody JS, Steiling K. "Interaction of cigarette exposure and airway epithelial cell gene expression." Annu Rev Physiol, 2011; 73:437-56.


Spira A, Steiling K. Topics in genetics and genomics: Gene Expression. In: UpToDate, Basow DS (Ed), UpToDate, Waltham MA, 2010.


Steiling K, Lenburg ME, Spira A. "Airway Gene Expression in Chronic Obstructive Pulmonary Disease."  Proc Am Thorac Soc,  2009;6:697-700.

Steiling K, Kadar AY, Bergerate A, Flanigon J, Sridhar S, Shah V, Ahmad QR, Brody JS, Lenburg ME, Steffen M, Spira A. "Comparison of proteomic and transcriptomic profiles in the bronchial airway epithelium of current and never smokers." PLoS ONE. 2009;4(4):e5043.


Steiling K, Ryan J, Brody JS*, Spira A*. "The field of tissue injury in the lung and airway." Cancer Prevention Research, 2008; 1(6):396-403. *contributed equally as senior author


Sridhar S, Schembri F, Zeskind J, Shah V, Gustafson A, Steiling K, Liu G, Dumas YM, Zhang X, Brody JS, Lenburg ME, Spira A. "Smoking-induced gene expression changes in the bronchial airway are reflected in nasal and buccal epithelium." BMC Genomics, 2008; 9:259.


Beane J, Sebastiani P, Whitfield TH, Steiling K, Dumas YM, Lenburg ME, Spira A. "A prediction model for lung cancer diagnosis that integrates genomic and clinical features."  Cancer Prevention Research, 2008; 1:56-64.


Spira A, Beane JE, Shah V, Steiling K, Liu G, Schembri F, Gilman S, Dumas YM, Calner P, Sebastiani P, Sridhar S, Beamis J, Lamb C, Anderson T, Gerry N, Keane J, Lenburg ME, Brody JS. "Airway epithelial gene expression in the diagnostic evaluation of smokers with suspect lung cancer." Nature Medicine, 2007; 13(3):361-6.