Post-doctoral research fellow in Translational Bioinformatics, Boston University


We are seeking a creative and motivated postdoctoral fellow to join our lab within the Department of Medicine and participate in our active research program aimed at using genomic approaches to understand the physiological response to tobacco-smoke and how this response contributes to diseases such as lung cancer and COPD. Current areas of interest include using high-throughput sequencing technology to discover tobacco-smoke-exposure- and disease-associated novel small RNAs and transcript variants, using network reconstruction algorithms to discover potential regulatory mechanisms, understanding how small regulatory RNAs such as microRNAs contribute to these processes, and developing sensitive and specific biomarkers able to diagnose disease and/or predict therapeutic outcome. Candidates should have or be close to obtaining a Ph.D. or equivalent degree in bioinformatics, computational biology, biostatistics, or a closely related field. Applicants must possess good communication skills and be fluent in both spoken and written English. Critical thinking, problem-solving abilities, and the ability to work semi-independently are required. Prior successful experience working with and developing algorithms for analyzing high dimensional biological datasets is required. Experience analyzing genome-wide gene-expression data is strongly desired. Experience R, Perl and MySQL is preferred. Current grants to the laboratory guarantee funding for the position through September 2012, and the selected candidate will be encouraged to seek independent fellowship funding. The selected candidate will be jointly supervised by Dr. Avrum Spira and Dr. Marc Lenburg, have access to the robust bioinformatics infrastructure at Boston University, and will receive a competitive salary and benefits package.


Interested individuals should send or email a letter of intent/cover letter, a CV with contact info for three references, and a 1-2 page description of relevant previous accomplishments to Ms. Erika Langer;; The Pulmonary Center, Boston University School of Medicine, 72 East Concord Street, R-304, Boston, MA 02118.